Email Address

info@macrocyclics.com

Phone Number

(469) 786-6060

Radiopharmaceutical Chelators

Radiopharmaceutical Chelators

Radiopharmaceuticals deliver focused doses of radiation by attaching a radioactive isotope (payload) to a targeting vector with affinity for cancerous cells. Our chelating agents support drug development programs all over the world.

GMP manufacturing

GMP manufacturing

Our advanced quality system allows efficient translation of new molecules and platforms into clinical research. Click to learn more about GMP production of our chelating agents, labeling precursors, and small molecule API's

Research Collaborations

See our publications and connect with our scientific team!

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About The Company

Macrocyclics, Inc. is a CDMO specializing in chelating agents for radiopharmaceuticals and nuclear medicine. The company provides custom synthesis, kilo-scale manufacturing, and bioconjugation services to accelerate early-stage pharmaceutical development.

Our Services

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Custom Organic Synthesis

Custom synthesis supports development of new linker mechanisms, drug conjugates, and labeling precursors. Our labs are specialized for small, multi-milligram projects, with equipment available for multi-gram to kilogram scale up.

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Analytical Services

Leading edge instrumentation and highly experienced scientific team ensure quality is designed into all aspects of the developmental process. Proficiencies include HPLC and HRMS (Q-TOF). Our analytical protocols can support stability extensions, impurity elucidation, and structural confirmation.

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Bioconjugation

Our team has experience with multiple conjugation mechanisms that target random lysine residues, interchain cysteine, and enzymatic tags. Complemented by our in-house suite of analytical instruments, we can efficiently build and evaluate multiple constructs for your program.

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